MCP servers › io.github.athril › agentic-target-evidence
MCP server · registry snapshot 2026-10-23 · last tested 2026-10-23
io.github.athril/agentic-target-evidence
Read-only biomedical evidence tools for drug-target validation: DepMap, gnomAD, OpenTargets, PubMed… — the publisher's description
Summary
io.github.athril/agentic-target-evidence is a local MCP server listed in the official MCP registry at version 0.1.4. On 2026-10-23 ProtocolProbe started its published package in an isolated sandbox in read-only mode and read its inventory: 42 tools, 0 resources and 0 prompts.
Record checks
4 of 5 record checks met · 4 do not apply
- met: Registry entry is active and says how to run it
- met: Source repository link opens
- met: Repository is not archived
- met: Code pushed to the repository in the 90 days before our check
- not met: Repository publishes a security policy (SECURITY.md)
- not applicable: Package names its licence with a standard (SPDX) identifier
- not applicable: The version the registry lists can be installed and is not withdrawn
- not applicable: npm package carries build provenance (attestation)
- not applicable: No known critical or high advisory in the package or its dependencies
- Not ranked by downloads: not an npm or PyPI package
- Not ranked by stars: 0 stars (ranked from 10)
From public records, not a safety rating. Each check with its reason · Is it safe to install?
Key facts
- Runs
- local package
- Transport
- standard input/output
- Package
- Docker (OCI)
- Repository
- public
- Tools
- 42
- Described as changing data
- 0 of 42 toolsAI-classified
- Mainly works on
- nothing outside itself: it only answers questionsAI-classified
- Topic
- science-health-and-educationAI-classified
- Last tested
- 2026-10-23
How fresh this is
- Live-tested
- yes, a real session (not a text-only review)
- Last tested
- 2026-10-23
- Mode
- read-only (no tool calls)
- Latest version
- 0.1.4, published 2026-10-05 (registry, as of the 2026-10-23 snapshot)
- First listed version
- 2026-10-05 (earliest version still in the registry; older removed versions would be earlier)
- Version history
- 2 versions listed, all on 2026-10-05; 2 in the 90 days before the 2026-10-23 snapshot.(versions still listed in the registry only)
Most recent 2 versions
0.1.4· 2026-10-050.1.3· 2026-10-05
- Registry data
- snapshot 2026-10-23
- Package and repository
- checked 2026-10-23
- Engine
- mcp-runtime-engine@0.1.0 · sdk@1.32.0
Changes since the last refresh
New in the registry: not in the list of 2026-10-04, listed on 2026-10-23 with version 0.1.4 (published 2026-10-05).
Source: the official MCP Registry list on 2026-10-04 and on 2026-10-23.
What it is
What does this server offer?
Observed inventoryWhat it mainly works on, as our AI model read its tool descriptions: nothing outside itself: it only answers questions.
None of its 42 tools are described as changing anything. For 2 the reading was uncertain, so no mark is shown.
- chembl_get_chemistryreads or searches
“Fetch ChEMBL drug-mechanism and bioactivity signals for a ChEMBL target id.”
2 inputs, 1 required
chembl_target_idstringrequiredgene_symbolstring
- clingen_get_validityreads or searches
“Fetch ClinGen gene-disease validity classifications for a gene.”
1 input, 1 required
gene_symbolstringrequired
- clinicaltrials_search_trialsreads or searches
“Search ClinicalTrials.gov v2 API for studies involving the gene and disease.”
3 inputs, 2 required
genestringrequireddiseasestringrequiredpopulationstring or null
- clinicaltrials_count_condition_trialsreads or searches
“Count trials for a disease/condition regardless of target gene or intervention.”
1 input, 1 required
conditionstringrequired
- depmap_get_dependencyreads or searches
“Fetch DepMap CRISPR gene effect and dependency scores for a gene.”
1 input, 1 required
gene_symbolstringrequired
- dgidb_get_gene_drug_interactionsreads or searches
“Fetch curated drug-gene interaction claims for a gene from DGIdb.”
3 inputs, 1 required
gene_symbolstringrequiredmax_resultsintegerapproved_onlyboolean
- dgidb_get_gene_categoriesreads or searches
“Fetch DGIdb gene-category annotations for a gene.”
1 input, 1 required
gene_symbolstringrequired
- encode_get_regulatory_coveragereads or searches
“Fetch regulatory-assay (ChIP-seq/DNase-seq/ATAC-seq) coverage at a gene locus.”
2 inputs, 1 required
gene_symbolstringrequiredgenomestring
- expression_atlas_get_differential_expressionreads or searches
“Fetch disease-vs-control differential expression for a gene from Expression Atlas.”
4 inputs, 1 required
gene_symbolstringrequireddiseasestringspeciesstringensembl_idstring
- gencc_get_validityreads or searches
“Fetch GenCC's per-submitter gene-disease validity classifications for a gene.”
1 input, 1 required
gene_symbolstringrequired
- gnomad_get_constraintreads or searches
“Fetch gnomAD gene-level LoF/missense/synonymous constraint (LOEUF, pLI, pRec, MOEUF, syn_z).”
1 input, 1 required
gene_symbolstringrequired
- gnomad_get_clinvar_variantsreads or searches
“Fetch ClinVar variants overlapping this gene from gnomAD's integrated dataset.”
2 inputs, 1 required
ensembl_idstringrequiredgene_symbolstring
Show 30 more tools
- gnomad_get_lof_variantsreads or searches
“Fetch observed high-confidence pLoF variants (natural knockouts) from gnomAD v4.”
2 inputs, 1 required
ensembl_idstringrequiredgene_symbolstring
- gtex_get_expressionreads or searches
“Fetch GTEx median tissue TPM and HPA protein localization for a gene.”
2 inputs, 1 required
gene_symbolstringrequiredensembl_idstring
- gwas_catalog_get_associationsreads or searches
“Fetch genome-wide significant GWAS associations for a gene from EBI GWAS Catalog.”
3 inputs, 1 required
gene_symbolstringrequiredp_thresholdnumbermax_associationsinteger
- impc_get_phenotypesreads or searches
“Fetch IMPC statistically significant knockout-mouse phenotype calls for a gene.”
1 input, 1 required
gene_symbolstringrequired
- hgnc_resolve_symbolreads or searches
“Resolve a gene symbol (including aliases/previous symbols) to its canonical HGNC record.”
1 input, 1 required
symbolstringrequired
- mondo_resolve_termreads or searches
“Resolve a disease name or existing ontology id to its MONDO term and cross-references.”
1 input, 1 required
name_or_idstringrequired
- hpo_get_phenotypesreads or searches
“Fetch HPO phenotype breadth/specificity and inheritance-mode hints for a gene.”
1 input, 1 required
gene_symbolstringrequired
- openalex_resolve_journalreads or searches
“Resolve a journal's OpenAlex quality signal from ISSN (preferred) or title.”
3 inputs
issnstringessnstringjournal_titlestring
“Search FDA drug labels for drugs mentioning the gene in mechanism of action or approved for the given indication.”
2 inputs, 2 required
gene_symbolstringrequiredindicationstringrequired
“Fetch FAERS adverse event summary for a drug name.”
1 input, 1 required
drug_namestringrequired
- openfda_count_indication_drugsreads or searches
“Count FDA-approved drugs for an indication, regardless of target gene.”
1 input, 1 required
indicationstringrequired
- opentargets_get_associationsreads or searches
“Fetch gene-disease association scores from the Open Targets Platform.”
2 inputs, 2 required
gene_idstringrequireddisease_idstringrequired
- opentargets_get_tractabilityreads or searches
“Fetch tractability evidence for a gene from the Open Targets Platform.”
1 input, 1 required
gene_idstringrequired
- opentargets_resolve_genereads or searches
“Resolve a gene symbol (e.g.”
1 input, 1 required
symbolstringrequired
- opentargets_resolve_diseasereads or searches
“Resolve a disease name (e.g.”
1 input, 1 required
namestringrequired
- opentargets_get_l2g_scoresreads or searches
“Fetch GWAS Locus-to-Gene (L2G) evidence for a gene-disease pair (OT Genetics).”
3 inputs, 2 required
gene_idstringrequireddisease_idstringrequiredmax_resultsinteger
- opentargets_get_colocalizationsreads or searches
“Fetch eQTL/pQTL ↔ GWAS colocalisations for a gene (OT Genetics).”
3 inputs, 1 required
gene_idstringrequiredh4_thresholdnumbermax_resultsinteger
- opentargets_get_known_drugsreads or searches
“Fetch known drugs targeting a gene from the Open Targets Platform.”
2 inputs, 1 required
gene_idstringrequiredmax_resultsinteger
- opentargets_get_safetyreads or searches
“Fetch safety liabilities for a gene from the Open Targets Platform.”
1 input, 1 required
gene_idstringrequired
- opentargets_get_mouse_phenotypesreads or searches
“Fetch mouse knock-out phenotypes for a gene from Open Targets (MGI/IMPC).”
1 input, 1 required
gene_idstringrequired
- orphanet_get_associationsreads or searches
“Fetch Orphanet rare-disease gene-disease associations for a gene.”
1 input, 1 required
gene_symbolstringrequired
- orphanet_get_prevalencereads or searches
“Fetch Orphanet disease-prevalence records for a set of OrphaCodes.”
1 input, 1 required
orphacodesarrayrequired
- project_score_getreads or searches
“Fetch Project Score (Sanger) CRISPR fitness/dependency data for a gene.”
1 input, 1 required
gene_symbolstringrequired
- pubmed_searchreads or searches
“Search PubMed using the NCBI E-utilities API.”
2 inputs, 1 required
querystringrequiredmax_resultsinteger
- pubmed_fetch_abstractreads or searches
“Fetch the abstract and metadata for a single PubMed article.”
1 input, 1 required
pmidstringrequired
- pubmed_fetch_pmc_recordreads or searches
“Return full-text availability info via PubMed Central.”
1 input, 1 required
pmidstringrequired
- spoke_get_gene_disease_associationsreads or searches
“Fetch SPOKE Disease-ASSOCIATES-Gene edges for a gene symbol.”
1 input, 1 required
gene_symbolstringrequired
- spoke_get_anatomy_expressionreads or searches
“Fetch SPOKE Anatomy-Gene expression edges for a gene symbol.”
1 input, 1 required
gene_symbolstringrequired
- uniprot_get_protein_profile
“Fetch the reviewed human UniProt protein profile (class, location, ChEMBL xref).”
1 input, 1 required
gene_symbolstringrequired
- uspto_search_patents
“Search PatentsView for patents referencing the gene and disease.”
2 inputs, 2 required
genestringrequireddiseasestringrequired
Each quoted sentence is the first sentence of the publisher’s own description. The kind of tool and the “changes data” mark are our AI model’s reading of that description, not something we tested: two differently worded runs had to agree, otherwise no label is shown, and nobody has checked them by hand. A tool without the “changes data” mark is described as only reading, searching or calculating, or the two runs did not agree. No tool was called. Read the publisher’s full description before relying on it. Inputs are the parameters in the tool's own input schema: name, declared type, whether it is required, and the first sentence of its description. Read 2026-10-23.
How well are its tools described?
Features #4 and #5
How clearly this server's own tool descriptions say what a tool does, and how consistent its tool list is. The first part is an AI model's yes/no reading of each description; the second part is counted. We do not turn it into a grade.
Descriptions
AI reading of each description
- Says what the tool does
- 100% of 40 tools
- Says what it returns
- 100% of 40 tools
- States limits, defaults or errors
- 17% of 36 tools
- Says when to use it
- 10% of 39 tools
- Items covered per tool
- 2.3 of 4 on average
Counted from the listing
- Parameters with a description
- 0% of 67
- Tools with a description
- 100% of 42
- Typical description length
- 135 characters
The tool set
Counted from the listing
- Tools
- 42
- Size of the list
- about 11,923 tokens for an agent to load (characters ÷ 4)
- Naming
- 42 of 42 names use snake_case
AI reading: easy to mix up
No pair found.
The AI items cover 40 of 42 tools: for a tool where two differently worded runs disagreed, that item is left out. They were not checked by hand, and no tool was called. “Easy to mix up” means two tools whose names or descriptions overlap without saying how they differ; the AI found none, comparing tools within groups of 40. We do not rate whether the tool set is complete or whether side effects are spelled out, because our AI reading of those was not reliable enough.
How do I add it to my client?
Config from the registry entry
From the Docker image ghcr.io/athril/agentic-target-evidence/mcp-gateway:v0.1.4
Our sandbox started this package on 2026-10-23 (a read-only session: no tool was called).
Add to CursorAn install link in the format Cursor documents, holding the Cursor config below. The command runs the publisher’s code on your machine.
Claude Desktop · claude_desktop_config.json (Settings → Developer → Edit Config)
{
"mcpServers": {
"agentic-target-evidence": {
"command": "docker",
"args": [
"run",
"-i",
"--rm",
"ghcr.io/athril/agentic-target-evidence/mcp-gateway:v0.1.4"
]
}
}
}Cursor · .cursor/mcp.json in a project, or ~/.cursor/mcp.json
{
"mcpServers": {
"agentic-target-evidence": {
"command": "docker",
"args": [
"run",
"-i",
"--rm",
"ghcr.io/athril/agentic-target-evidence/mcp-gateway:v0.1.4"
]
}
}
}VS Code · .vscode/mcp.json
{
"servers": {
"agentic-target-evidence": {
"type": "stdio",
"command": "docker",
"args": [
"run",
"-i",
"--rm",
"ghcr.io/athril/agentic-target-evidence/mcp-gateway:v0.1.4"
]
}
}
}VS Code (command line) · Bash or zsh terminal (macOS, Linux)
code --add-mcp '{"name":"agentic-target-evidence","type":"stdio","command":"docker","args":["run","-i","--rm","ghcr.io/athril/agentic-target-evidence/mcp-gateway:v0.1.4"]}'Claude Code
claude mcp add --transport stdio agentic-target-evidence -- docker run -i --rm ghcr.io/athril/agentic-target-evidence/mcp-gateway:v0.1.4
Try it in the MCP Inspector · runs on your machine, opens in your browser · Node 22.19+
npx @modelcontextprotocol/inspector@2.11.0 -- docker run -i --rm ghcr.io/athril/agentic-target-evidence/mcp-gateway:v0.1.4
- Optional settings the entry also lists (left out above): MCP_TRANSPORT, NCBI_API_KEY, USPTO_API_KEY.
- This runs the publisher's code on your machine (docker). Read its README first.
- The MCP Inspector lists the server's tools, resources and prompts; a tool you call there runs for real.
Built from the server's registry entry with each client's documented format (checked 2026-10-14; the Cursor link and the VS Code command 2026-10-19; the MCP Inspector command 2026-10-21). Values in < > are yours to fill in; this page never contains a key. Where the server needs a setting the entry does not declare, it can still fail to start.
Does the registry listing match what we found?
Feature #6The registry verifies a package once, when it is published, and does not re-check it. A difference below is about the listing, not a judgement of the publisher.
| Registry says | We found | Result | Source · date |
|---|---|---|---|
| Published package can be started | Started and answered | matches | our test · 2026-10-23 |
| Repository github.com/athril/agentic-target-evidence | Opens publicly | matches | api.github.com · 2026-10-23 |
Who made it?
Feature #7 · lineage
Facts about the publisher. We do not turn them into a trust score.
- Namespace
- io.github.athril
- GitHub owner
- a personal account (athril)
- Repository
- github.com/athril/agentic-target-evidence
- Stars
- 0
- Repository age
- 91–180 days
- Last push
- 0–30 days ago
- Archived
- no
- Security policy
- none found (we looked for SECURITY.md in the repository and in its owner’s .github repository)
Source: the registry entry and api.github.com · 2026-10-23; security policy read from GitHub · 2026-10-23.
Publish this server? Run these checks against it yourself before release, from your own machine: a server the command starts, or your own server at its URL after a one-time proof that you control it: npx protocolprobe-selftest.
Choosing
Record checks
Public records · not a safety rating4 of 5 record checks met · 4 do not apply
- Not ranked by downloads: not an npm or PyPI package
- Not ranked by stars: 0 stars (ranked from 10)
- MetRegistry entry is active and says how to run itActive, with a package or a remote address.
- MetSource repository link opensThe linked GitHub repository is public.
- MetRepository is not archivedNot archived.
- MetCode pushed to the repository in the 90 days before our checkLast push 0-30 days before our check.
- Not metRepository publishes a security policy (SECURITY.md)No SECURITY.md in the places GitHub reads it from.
- Does not applyPackage names its licence with a standard (SPDX) identifierNot an npm or PyPI package.
- Does not applyThe version the registry lists can be installed and is not withdrawnNot an npm or PyPI package.
- Does not applynpm package carries build provenance (attestation)PyPI packages have no npm-style attestation.
- Does not applyNo known critical or high advisory in the package or its dependenciesNot an npm or PyPI package.
Read from public records only: the registry entry, npm/PyPI, GitHub and advisory databases, checked 2026-10-23. No tool was called. Only “met” and “not met” are counted, so the total differs between servers; a check that does not apply or that we could not run is listed, never counted against it. It is not a safety rating. How each check works · Leaderboards
Common questions about io.github.athril/agentic-target-evidence
Answered from the data aboveIs io.github.athril/agentic-target-evidence safe to install?
We do not rate servers as safe or unsafe. 4 of its 5 applicable record checks are met (facts from public records, each listed on this page). What the records show: Its source repository opens publicly. Its repository had a push in the last 90 days. These are facts with their sources on this page, not a safety guarantee, and we did not run its tools.
Has io.github.athril/agentic-target-evidence been security tested?
Partly. 2 of the 12 checks that apply to it were exercised. We started the package in an isolated sandbox and read what it declares, but this test round was read-only, so its tools were not called. No security verdict is published before verification.
What can io.github.athril/agentic-target-evidence do?
It lists 42 tools. In our AI model's reading of their descriptions (two runs had to agree, nobody checked it by hand), they include tools that read or search. We did not call any tool, so this describes the text, not the behaviour.
Can io.github.athril/agentic-target-evidence change or delete data?
None of its 42 tools is described as changing anything (our AI model's reading of the descriptions; nobody checked it by hand). We did not call any tool.
Does io.github.athril/agentic-target-evidence publish a security policy?
We found no SECURITY.md in its repository (root, .github/ or docs/) or in its owner's .github repository.
Where is the source code of io.github.athril/agentic-target-evidence?
In github.com/athril/agentic-target-evidence, which opens publicly.
Found this page useful?
Anonymous · no sign-inA quick, anonymous reaction — no account, no email. One per kind from your browser. The tally updates when the page is next refreshed, and it is only a rough count, never a safety rating or a measured number of people.
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Active servers whose topic is also “science-health-and-education” and that have at least one tool of the same kind; most kinds in common first, then most GitHub stars. The topic and the tool kinds are an AI model's reading of the publishers' descriptions, not checked by hand. Similar is not a recommendation.
Compare with another server
Side by side: registry entry, our read-only session, the tools and the 18 classification fields. Same values as each page; no score.
Security testing
What did we test, and what did we leave out?
18 checks · features #1, #2
Not probed (read-only run)
We started the package in an isolated sandbox and read what it declares, but this test round was read-only, so its tools were not called. No security score is given; a check we did not run is never counted as passed.
- Inventory: exercised
- Hidden instructions: exercised
- Real execution: not run · our policy
- Secret leak: not run · nothing to check it against
- Internal addresses: not run · our policy
- Unconfirmed changes: not run · our policy
- Bad input: not run · our policy
- Model requests: not run · nothing to check it against
- Sensitive questions: not run · nothing to check it against
- Folder boundary: not run · our policy
- Log leaks: not run · nothing to check it against
- Hidden content: not run · nothing to check it against
- Fake assistant turns: not applicable
- Token passthrough: not applicable
- Token audience: not applicable
- Sign-in redirect: not applicable
- Consent handling: not applicable
- Sign-in metadata: not applicable
2 exercised10 not run (reason given)6 not applicable
Each check ends in exactly one state: exercised, not run (with the reason), or not applicable (with the reason). 2 of the 12 checks that apply to it were exercised. We do not publish security-check outcomes for named servers.
- 1Inventory
tool-listReads the declared tools, resources and prompts.exercised - 2Hidden instructions
description-poisoningLooks for hidden instructions in tool descriptions.exercised
- 3Real execution
real-executionCalls a tool and checks what really happens.This check calls the package's tools. This test round was read-only, so no tool was called; tools can act on outside services with the publisher's or a user's account.not run · our policy - 4Secret leak
canary-leakPlants a fake secret and checks whether it leaks.This check needs at least one successful tool call to have something to check, and no tool was called.not run · nothing to check it against - 5Internal addresses
ssrfChecks whether a tool can be steered to internal addresses.This check calls the package's tools. This test round was read-only, so no tool was called; tools can act on outside services with the publisher's or a user's account.not run · our policy - 6Unconfirmed changes
write-without-confirmationChecks whether tools that change data act without asking.This check calls the package's tools. This test round was read-only, so no tool was called; tools can act on outside services with the publisher's or a user's account.not run · our policy - 7Bad input
error-handlingSends bad input and watches how the server answers.This check calls the package's tools. This test round was read-only, so no tool was called; tools can act on outside services with the publisher's or a user's account.not run · our policy - 8Model requests
samplingChecks whether the server asks the client's model to act for it.This check needs at least one successful tool call to have something to check, and no tool was called.not run · nothing to check it against - 9Sensitive questions
elicitation-sensitive-dataChecks whether the server asks users for sensitive data.This check needs at least one successful tool call to have something to check, and no tool was called.not run · nothing to check it against - 10Folder boundary
root-boundaryChecks whether the server reaches outside the folders it was given.This check calls the package's tools. This test round was read-only, so no tool was called; tools can act on outside services with the publisher's or a user's account.not run · our policy - 11Log leaks
logging-side-channelChecks whether log messages carry data they should not.This check needs at least one successful tool call to have something to check, and no tool was called.not run · nothing to check it against - 12Hidden content
audience-hidingChecks resources that hide content from the user.This check needs content the server returns, and nothing was read or called.not run · nothing to check it against
- 13Fake assistant turns
fake-assistant-turnChecks prompts that pose as the assistant's own words.The server exposes no prompts.not applicable - 14Token passthrough
token-passthroughChecks whether the server forwards a user's token to other services.The server runs locally over standard input/output, so there is no sign-in flow to check.not applicable - 15Token audience
token-audience-validationChecks whether tokens meant for another service are accepted.The server runs locally over standard input/output, so there is no sign-in flow to check.not applicable - 16Sign-in redirect
open-redirectChecks the sign-in redirect for abuse.The server runs locally over standard input/output, so there is no sign-in flow to check.not applicable - 17Consent handling
confused-deputyChecks consent handling when one service acts for another.The server runs locally over standard input/output, so there is no sign-in flow to check.not applicable - 18Sign-in metadata
oauth-url-schemeChecks the published sign-in metadata for unsafe URLs.The server runs locally over standard input/output, so there is no sign-in flow to check.not applicable
Source: our own test in an isolated sandbox, 2026-10-23, mcp-runtime-engine@0.1.0. Which checks count and why follows our published scoring model.
What happened during the test?
Feature #8
The steps in order, as the test record holds them.
- 0 msStarted the published package in an isolated sandbox (read-only mode)
- 8,860 msConnected after 0 redirects.
- Read the inventory: 42 tools, 0 resources, 0 prompts.
- 20,187 msFinished: 2 checks exercised.
Reference
How is it classified?
18 fields
One value per field, each with its source. Fields written by AI models are marked. A field with no value says why.
“Not stated” means the source did not state it; “does not apply” means it does not apply to this kind of server; “our limit” means our own lookup failed. A linked value opens the directory filtered to the same value.
Cite or correct this page
Sources and corrections
Suggested citation
ProtocolProbe. “io.github.athril/agentic-target-evidence: MCP server record.” Data checked 2026-10-23. https://protocolprobe.com/mcp/servers/io.github.athril/agentic-target-evidence
Figures are valid for the date shown. Our facts on this page are CC BY 4.0: reuse them with a link and the check date. Quoted text (the publisher’s descriptions, website quotes, tool names) is not ours to license.
As JSON: this record in the API · API documentation.
Badge for your README
[](https://protocolprobe.com/mcp/servers/io.github.athril/agentic-target-evidence)
It shows this server's record-check count: facts from public records, no tool called. It is not a security rating or a pass. It links here and updates after each data reload.
Something wrong, or is this yours?
If a fact here is wrong, tell us and we will re-check it. If you operate this server, you can run our checks on it yourself with the free self-test command; we call no server’s tools ourselves for anything shown here.
Write to hello@protocolprobe.com · corrections log · methodology